Necrotic foci in the spleen of a 3-year-old Rottweiler in a case of metastatic histiocytic sarcoma. Additionally to focal necrosis, the spleen exhibited extensive deposits of hyaline material, clearly visible in the right-side image (H&E, 100x). Staining with Congo Red revealed the substance to be amyloid.

 






 
 
 
 
 

 

 
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